基本信息
文件名称:EGFR-IN-149-生命科学试剂-MCE.pdf
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更新时间:2025-03-19
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文档摘要

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Inhibitors?ScreeningLibraries?Proteins

www.MedChemE

EGFR-IN-149

Cat.No.:HY-169570

CASNo.:401638-52-6

分?式:C??H??N?OS

分?量:297.37

作?靶点:EGFR

作?通路:JAK/STATSignaling;ProteinTyrosineKinase/RTK

储存?式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

?物活性EGFR-IN-149(Compound3-OH)是?种EGFR抑制剂(IC50:0.42nM)。

REFERENCES

[1].PéterBáNHEGYI,etal.Therapeuticapplicationoftriciclicaromaticandsaturatedbenzo(4,5)thieno-(2,3-d)pyrimidinederivates,aswell

astheirtherapeuticallyacceptablesalts.Patent.WO2009104027A1

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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1/1MasterofBioactiveMolecules—您?边的抑制剂?师